Первичная кожная диффузная В-крупноклеточная лимфома, тип нижних конечностей

A rare, aggressive, primary cutaneous B-cell lymphoma characterized by rapidly progressive, red to bluish, often ulcerating, nodular tumors predominantly involving the lower legs. Histology shows sheets of centroblasts and immunoblasts that spare the epidermis, but infiltrate the dermis and subcutaneous tissues, and often disseminate extracutaneously. The neoplastic cells typically express CD2, CD79a, Bcl-2, MUM-1, and FOXP1, but are negative for CD1.