Острый миелобластный лейкоз с созреванием

Определение

A rare, acute myeloid leukemia characterized by evidence of granulocytic maturation and more than 2% of blast cells in the bone marrow and/or peripheral blood. The maturing non-blast granulocytic cells account for greater than or equal to 1% and monocytic cells less than or equal to 2% of the bone marrow cells. Various degrees of anemia, thrombocytopenia, or pancytopenia are present. Frequent clinical manifestations include fatigue, fever, bleeding disorders, and organomegaly, especially hepatosplenomegaly.