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Scientific Reports (IF 4,122, Q1) published an article by the FSBI RCMG researchers on Clinical relevance of somatic mutations in gastric cancer

Scientific Reports (impact-factor 4.122, Q1) published an article by the Epigenetics Laboratory researchers (the Lab Head is V.V. Strelnikov, Doctor of biological science):

«Clinical relevance of somatic mutations in main driver genes detected in gastric cancer patients by next-generation DNA sequencing».

Authors: Marina V Nemtsova, Alexey I Kalinkin, Ekaterina B Kuznetsova, Irina V Bure, Ekaterina A Alekseeva, Igor I Bykov, Tatiana V Khorobrykh, Dmitry S Mikhaylenko, Alexander S Tanas, Sergey I Kutsev, Dmitry V Zaletaev, Vladimir V Strelnikov

«Clinical relevance of somatic mutations in main driver genes detected in gastric cancer patients by next-generation DNA sequencing».

Gastric cancer is one of the most common oncological diseases, ranking fifth in the world in incidence and third in mortality among all malignant neoplasms. Until recently, the classification of gastric cancer primarily based on histological criteria. This study described the spectra of mutations of genes involved in carcinogenesis of gastric cancer in various histological types of tumors, and carried out a search for new mutations in these genes in Russian patients.

https://www.nature.com/articles/s41598-020-57544-3.pdf

doi: 10.1038/s41598-020-57544-3